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😇😫😩 Pharmacologic class: Carbamate derivative
😇😫😩 Therapeutic class: Centrally acting skeletal muscle relaxant
😇😫😩 Controlled substance schedule IV (in some states)
😇😫😩 Pregnancy risk category C
😇😫😩 Unknown. May modify central perception of pain without modifying pain reflexes. Skeletal muscle relaxation may result from sedative properties or from inhibition of activity in descending reticular formation and spinal cord.
😇😫😩 Tablets: 250 mg, 350 mg
Indications and dosages
😇😫😩 ➣ Adjunctive treatment of muscle spasms associated with acute painful musculoskeletal conditions
😇😫😩 Adults: 350 mg P.O. q.i.d.
😇😫😩 ➣ Relief of discomfort associated with acute painful musculoskeletal conditions
😇😫😩 Adults: 250 to 350 mg P.O. t.i.d. and at bedtime
😇😫😩 • Hypersensitivity to drug or meprobamate
😇😫😩 • Porphyria or suspected porphyria
😇😫😩 Use cautiously in:
😇😫😩 • severe hepatic or renal disease
😇😫😩 • history of substance abuse
😇😫😩 • pregnant or breastfeeding patients
😇😫😩 • children ages 12 and younger.
😇😫😩 • Give last daily dose at bedtime.
😇😫😩 • Administer with food if GI upset occurs.
😇😫😩 • If patient can't swallow tablets, mix with syrup, chocolate, or jelly.
😇😫😩 CNS: dizziness, drowsiness, agitation, ataxia, depression, headache, insomnia, vertigo, tremor, depression
😇😫😩 CV: hypotension, tachycardia
😇😫😩 GI: nausea, vomiting, epigastric distress
😇😫😩 Hematologic: eosinophilia, leukopenia
😇😫😩 Respiratory: asthma attacks
😇😫😩 Skin: flushing (especially of face), rash, pruritus, erythema multiforme
😇😫😩 Other: hiccups, fever, psychological drug dependence, anaphylactic shock
😇😫😩 Drug-drug.Antihistamines, opioids, sedative-hypnotics: additive CNS depression
😇😫😩 Drug-diagnostic tests.Eosinophils: increased count
😇😫😩 Drug-herbs.Chamomile, hops, kava, skullcap, valerian: increased CNS depression
😇😫😩 Drug-behaviors.Alcohol use: increased CNS depression
😇😫😩 • When giving to breastfeeding patient, watch for signs of sedation and GI upset in infant.
😇😫😩 • Monitor range of motion, stiffness, and discomfort level.
😇😫😩 • Know that drug is metabolized to meprobamate. Monitor for drug dependence, especially in patients with history of substance abuse.
😇😫😩 • Tell patient that psychological drug dependence may occur.
😇😫😩 • Instruct patient to avoid over-the-counter drugs and alcohol, because they may increase CNS depression.
😇😫😩 • Caution patient to avoid driving and other hazardous activities until he knows how drug affects concentration and alertness.
😇😫😩 • As appropriate, review all other significant and life-threatening adverse reactions and interactions, especially those related to the drugs, tests, herbs, and behaviors mentioned above.
See also: body.
See also: body.
Soma®Carisoprodol and meprobamate, see there.
See also: body
somathe body of an animal excluding the germinal cells that give rise to the gametes.
Patient discussion about soma
😇😫😩 Q. what are the side effects from taking soma and flexerill together? the person who takes it is almost comatos for a couple of hours. What is a substition?